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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Immunohistochemical localization of NGF, BDNF, and their receptors in a normal and AMD-like rat retina

Fig. 2

mBDNF and TrkB expression in the rat retina during aging and development of AMD-like retinopathy. a Double-label immunofluorescent staining of mBDNF (green) and TrkB (red) in the retina of OXYS and Wistar rats (n = 4) at various ages. b Double-label immunofluorescent staining of NeuN (green) and mBDNF (red) in the retina of 3-month-old OXYS and Wistar rats. There was no mBDNF expression in the retinal ganglion cells of OXYS rats. c Double-label immunofluorescent staining of vimentin (red) and mBDNF (green) in the retina of 3-month-old OXYS and Wistar rats. There was mBDNF expression in the Muller glia of both OXYS and Wistar rat retinas. Nuclei were stained blue using DAPI. Abbreviations: GCL, ganglion cell layer; INL, inner nuclear layer; ONL, outer nuclear layer

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