|
Gene
|
CpG
|
CIMP-H
|
CIMP-L
|
Cluster 3
|
Cluster 4
|
All
|
All
|
All
|
|---|
| | |
Δβ
|
logFC
|
Δβ
|
logFC
|
Δβ
|
logFC
|
Δβ
|
logFC
|
Δβ
|
logFC
|
Changed Methylation (n = 381)
|
Changed Expression (n = 359)
|
|---|
|
CEP55
|
cg25314624
|
−0.36
|
1.62
|
−0.38
|
1.38
|
−0.38
|
1.24
|
−0.35
|
1.18
|
0.37
|
1.32
|
376 (98.7%)
|
341 up (95.0%)
|
|
FOXD3
|
cg15617155
|
0.31
|
−4.28
|
0.31
|
−3.21
|
0.33
|
−2.70
|
0.32
|
−2.53
|
0.40
|
− 3.05
|
373 (97.9%)
|
353 down (98.3%)
|
|
FOXF2
|
cg12221475
|
0.34
|
−2.55
|
0.41
|
−2.09
|
0.39
|
−1.85
|
0.41
|
−1.58
|
0.39
|
−1.96
|
309 (81.1%)
|
355 down (98.9%)
|
|
GNAO1
|
cg00866976
|
0.35
|
−4.04
|
0.39
|
−3.18
|
0.37
|
−2.69
|
0.41
|
− 2.04
|
0.38
|
− 2.88
|
304 (79.8%)
|
352 down (98.1%)
|
| |
cg10273340
|
0.40
| |
0.44
| |
0.42
| |
0.46
| |
0.43
| |
306 (80.3%)
| |
|
GRIA4
|
cg00343633
|
0.52
|
−3.12
|
0.55
|
−2.59
|
0.55
|
−2.19
|
0.51
|
−2.03
|
0.54
|
−2.41
|
375 (98.4%)
|
352 down (98.1%)
|
| |
cg03225817
|
0.44
| |
0.49
| |
0.49
| |
0.45
| |
0.47
| |
367 (96.3%)
| |
| |
cg07972135
|
0.44
| |
0.50
| |
0.51
| |
0.47
| |
0.49
| |
369 (96.9%)
| |
| |
cg23559689
|
0.43
| |
0.48
| |
0.47
| |
0.46
| |
0.46
| |
375 (98.4%)
| |
|
KCNA5
|
cg16897114
|
0.34
|
−2.81
|
0.35
|
−2.24
|
0.35
|
−1.97
|
0.34
|
−1.32
|
0.35
|
−2.02
|
358 (94.0%)
|
354 down (98.6%)
|
- CIMP the CpG island methylator phenotype, logFC logarithm of fold change, Δβ difference in average beta value between tumor and normal mucosa samples, n number of samples
