Skip to main content

Table 5 Methylation and gene expression on our dataset. P-value was calculated between ΔCt of tumor and ΔCt of normal mucosa samples

From: Genes CEP55, FOXD3, FOXF2, GNAO1, GRIA4, and KCNA5 as potential diagnostic biomarkers in colorectal cancer

Gene Expression dataset (n = 25) Methylation dataset (n = 115)
Methylation Expression logFC (p-value) Methylation
CEP55 100% Unmethylated 100% up-regulated 7.47 (< 0.001) 97.3% unmethylated
FOXD3 96% methylated 68% down-regulated −0.66 (0.027) 100% methylated
FOXF2 88% methylated 76% down-regulated −1.33 (0.021) 90.2% methylated
GNAO1 100% methylated 96% down-regulated −4.78, (<  0.001) 100% methylated
GRIA4 96% methylated 95.2% down-regulated −3.25 (<  0.001) 97.3% methylated
KCNA5 100% methylated 84% down-regulated −2.81 (< 0.001) 99.1% methylated
  1. n number of samples, logFC logarithm of fold change