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Table 5 Methylation and gene expression on our dataset. P-value was calculated between ΔCt of tumor and ΔCt of normal mucosa samples

From: Genes CEP55, FOXD3, FOXF2, GNAO1, GRIA4, and KCNA5 as potential diagnostic biomarkers in colorectal cancer

Gene

Expression dataset (n = 25)

Methylation dataset (n = 115)

Methylation

Expression

logFC (p-value)

Methylation

CEP55

100% Unmethylated

100% up-regulated

7.47 (< 0.001)

97.3% unmethylated

FOXD3

96% methylated

68% down-regulated

−0.66 (0.027)

100% methylated

FOXF2

88% methylated

76% down-regulated

−1.33 (0.021)

90.2% methylated

GNAO1

100% methylated

96% down-regulated

−4.78, (<  0.001)

100% methylated

GRIA4

96% methylated

95.2% down-regulated

−3.25 (<  0.001)

97.3% methylated

KCNA5

100% methylated

84% down-regulated

−2.81 (< 0.001)

99.1% methylated

  1. n number of samples, logFC logarithm of fold change