Fig. 6

PacBio Sequencing of centromeric K111 in Chr 21, 22 and Human DNA. A squished plot of the PacBio sequences generated from the 3′ side of K111 in the hamster/human chromosome 21 and 22 hybrids, as well as normal human DNA. The squished map only shows indels (black dots) that represent subsets of K111 proviruses that are different from the deposited K111 sequence. Numerous shared indels can be seen in many of the sequences, suggestive of the presence of hundreds of unique K111 proviruses in these chromosomes. There appear to be some unique sequences in chromosome 21 compared to chromosome 22. The squished map of sequences amplified from human DNA display sequence patterns similar to those found in Chr 21 and 22