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Table 3 Frequency of Detection of −/− K111 in DNA in Caucasian patients with different diseases

From: Structural variation of centromeric endogenous retroviruses in human populations and their impact on cutaneous T-cell lymphoma, Sézary syndrome, and HIV infection

Disease Origin No. Tested −/− K111 Frequency of −/− K111 (%) X2 P value
Skin Diseases  
 Psoriasis Michigan 123 19 15.4 0.0017 ns
HIV Infection
 HIV LTNP MACS 25 5 20 0.3046 ns
Michigan, New York 11 5 45.5 6.3308 0.0118
 Total LTNP   36 11 30.55 4.39
6.691
0.0366
0.0097*
 Intermediate MACS 29 6 20.7 0.4593 ns
Michigan, New York 3 0 0 0.554 ns
 Total Intermediate   32 6 18.75 0.192 ns
 Rapid AIDS MACS 30 3 10 0.6362 ns
New York, Michigan 17 1 5.9 1.16 ns
 Total Rapid AIDS   47 4 8.5 1.526 ns
 Unclassified New York, Michigan, MACS 49 5 10.2 0.896 ns
 Total   164 25 15.2 0.009 ns
Solid tumors
 Breast Cancer New York, Michigan 53 2 9.4 1.26 ns
Lymphomas
 Hodgkin Michigan 3 0 0 0.554 ns
 Mantle cell Michigan 6 1 16.5 0.048 ns
 Marginal zone Michigan 5 1 20 0.0699 ns
 DLBCL Michigan 17 1 5.9 0.2806 ns
 Follicular Michigan 23 3 13.0 0.1034 ns
 CLL Michigan 11 2 18.2 0.0506 ns
 Total   65 8 12.3 0.406 ns
Autoimmune Disorders
 Takayasu Turkey 30 3 10 0.6362 ns
 Lupus Michigan 38 7 18.4 0.1772 ns
  1. The star indicates a significant difference of the frequency of detection of the −/−K111 genotype between the LTNP and Rapid AIDS patients