Structural variation of centromeric endogenous retroviruses in human populations and their impact on cutaneous T-cell lymphoma, Sézary syndrome, and HIV infection

Table 4 Frequency of Detection of −/−K111 in DNA from African and African American patients with different diseases

Disease	Origin	No. Tested	−/−K111	Frequency of −/−K111 (%)	X ²	P value
African
Healthy	Nigeria	127	3	2.36
Healthy	Nigeria	127	3	2.36	14.583	0.00001#
African Breast Cancer	Nigeria	139	2	1.44	0.307	ns
African Breast Cancer	Nigeria	139	2	1.44	18.2223	0.00002#
Total African		266	5	1.8		0.00001#
HIV/AIDS	Michigan, New York	6	1	16.6	0.216	ns
unclassified	Michigan, New York	5	0	0	0.564	ns
HIV LTNP	Baltimore	18	1	5.6	0.340	ns
DLBCL	Michigan	3	1	33	1.41	ns
CTCL	Michigan	4	0	0	0.452	ns
Breast Cancer	Michigan	3	0	0	0.574	ns
Total African American all diseases		39	3	7.6	1.821	ns

Statistical analysis was determined between healthy individuals and patients of the same ethnicity. # indicates significant differences between healthy Caucasian individuals and healthy African individuals or African patients with breast cancer

ISSN: 1755-8794