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Table 1 Comparison between tissues of HCC patients. Ratio of the averages and p value of the paired samples t-test

From: Entropy of mitochondrial DNA circulating in blood is associated with hepatocellular carcinoma

 

Blood vs Normal liver

p value

Blood vs Tumor

p value

Normal liver vs Tumor

p value

Number of patients

25

N/A

277

N/A

81

N/A

Number of reads (log10)

1.02

8.78E-01

0.99

7.82E-01

1.02

7.82E-01

mtDNA average depth

0.14

9.96E-05

0.49

8.30E-12

1.86

6.68E-04

mtDNA total entropy

0.49

1.40E-03

0.75

2.22E-03

1.26

2.44E-01

Percentage of the mtDNA genome covered

0.98

1.06E-06

1.00

1.95E-06

1.00

4.87E-04

Percentage of all reads that map to the mtDNA genome

0.19

1.45E-06

0.50

2.02E-12

1.72

3.33E-04

Number of polymorphic sites.

0.18

3.17E-04

0.50

8.29E-04

2.09

2.52E-03

Number of different sites (p < 0.05)

468

N/A

319

N/A

492

N/A