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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Topological integration of RPPA proteomic data with multi-omics data for survival prediction in breast cancer via pathway activity inference

Fig. 3

Structure of the unified pathway network. A colored node indicates that the gene is included in the corresponding omics profile, and a white node indicates that it is included in a pathway gene set although not in omics profile. A node with a bold borderline represents that the gene appears in both corresponded profile and RNA-Seq profile. In this structure, the inter-relation edges are assigned between the nodes containing the same gene feature in RNA-Seq profile, and the edge direction is set from a proteome network to a transcriptome network or from an epigenome network to a transcriptome network

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