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Table 3 ss-DEG Methods Recommendations: Single-subject studies of two-sample conditions without replicates

From: Evaluating single-subject study methods for personal transcriptomic interpretations to advance precision medicine

  Combinations of accuracies
15% < DEGs < 30% 55% < DEGs < 70%
Precision (%)→ > 90% > 70% 50 > 90%
Recall→ (>%) 90 70 50 25 90 70 50 25 90 70 50 25 90 70 50 25
Methods
 Ensemble
 NOISeq
 DEGseq
 Mixture Model
 edgeR
 iDEG
 DESeq
 DESeq2
  1. = recommended; ✗ = not recommended