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Table 5 The results of basal-like type specific regulatory modules obtained by CONFIGURE

From: CONFIGURE: A pipeline for identifying context specific regulatory modules from gene expression data and its application to breast cancer

Regulatory Module

Target Gene

FIS

Status

Evidence

POU5F1(-)

TOX3

0.1328

down-regulated

[38, 39]

 

RALGPS2

   
 

FUT8

   
 

HMGCR

   
 

FOXA1

   

ZIC1(-)

XBP1

0.1072

down-regulated

 
 

OVOL1

   
 

SLC1A4

   
 

SMAD7

   
 

CNTN1

   

RARA(+)

RARA

0.0827

down-regulated

 
 

STARD3

   
 

PLEKHH3

   
 

MAG

   
 

PCGF2

   

E2F3(+)

E2F3

0.0667

up-regulated

 
 

ANP32E

   
 

GEN1

   
 

SYNCRIP

   
 

BEND3

   

GATA6(-)

MAST4

0.058

down-regulated

[40]

 

PDE6B

   
 

ROBO2

   
 

KIF5A

   
 

ABI2

   

PHOX2B(+)

PHOX2B

0.0454

up-regulated

 
 

DDC

   
 

MSGN1

   
 

AKR1D1

   
 

FABP7

   

GLI3(-)

PPIF

0.0447

up-regulated

[41]

 

ELF5

   
 

ORAI1

   
 

POR

   
 

HMGA1

   

ETV6(+)

PHB2

0.0346

up-regulated

 
 

NCAPD2

   
 

VANGL2

   
 

PLEKHA5

   
 

ETV6

   

SRF(-)

PAIP2

0.0344

down-regulated

[37, 42]

 

ERLEC1

   
 

NECAP1

   
 

SCRN3

   
 

ZFP62

   

PLAGL1(-)

SLC25A17

0.0327

down-regulated

 
 

NPBWR2

   
 

PTK6

   
 

SYCE2

   
 

HN1L

  Â