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Table 1 Simulation study settings

From: Meta-Qtest: meta-analysis of quadratic test for rare variants

Scenario

Population

Sample Size

Covariates

Study 1

Study 2

Study 3

Study 1

Study 2

Study 3

1

EUR

1600

2200

3200

(x1, x2)

(x1, x2)

(x1,x2)

2

EUR

1600

2200

3200

(x1)

(x1, x2)

(x1,x2,x3)

3

EUR + AA

1600

2200

3200

(x1)

(x1, x2)

(x1,x2,x3)

4

EUR

2400

2400

2400

(x1, x2)

(x1, x2)

(x1,x2)

5

EUR

2400

2400

2400

(x1)

(x1, x2)

(x1,x2,x3)

6

EUR + AA

2400

2400

2400

(x1)

(x1, x2)

(x1,x2,x3)

  1. EUR + AA denotes that population of first and second study is European and the population of Study3 is African-American