Table 5 Meta-Analysis Results for Testing the Rare Variants Effects on Systolic Blood Pressure
From: Meta-Qtest: meta-analysis of quadratic test for rare variants
Meta-Analysis | GENE | ||
|---|---|---|---|
Method | Test type | PCDHA9 (CHR 5) | KCNA5 (CHR 12) |
meta Q tests | Het-meta-Q1 | 6.18E-01 | 1.03E-01 |
Het-meta-Q2 | 4.75E-06 | 1.19E-05 | |
Het-meta-Q3 | 7.34E-06 | 2.41E-05 | |
meta SKAT | Hom-meta-SKAT | 3.93E-03 | 5.03E-04 |
Het-meta-SKAT | 3.72E-03 | 1.68E-04 | |
Hom-meta-SKAT-O | 7.65E-03 | 1.13E-03 | |
Het-meta-SKAT-O | 7.60E-03 | 4.67E-04 | |
Other methods | Meta-burden | 7.97E-01 | 2.59E-01 |
Fisher’s method (Q3) | 8.18E-06 | 3.06E-05 | |
Score method (Q3) | 2.23E-04 | 1.31E-05 | |