Fig. 2

Result of power analysis. Columns and rows represent different phenotypic correlations (0.25 and 0.5) and proportions of significant genes within the causal pathway (10 and 20%). For each plot, estimated statistical powers from 300 simulation datasets are shown with combinations of gene-level effects (0.1, 0.2, 0.5 and 1) and pathway-level effects (0.15, 0.2 and 0.25)