Skip to main content

Table 1 Biological processes (Gene Ontology terms) associated with the 42 differentially expressed miRNAs

From: Identification of potential biomarkers for diagnosis of pancreatic and biliary tract cancers by sequencing of serum microRNAs

Biological process Count % P-value Fold Enrichment Bonferroni
transcription, DNA-templated 581 13.30 4.86E-13 1.29 3.52E-09
positive regulation of transcription, DNA-templated 188 4.30 4.20E-12 1.58 3.04E-08
regulation of transcription, DNA-templated 448 10.25 2.78E-10 1.29 2.01E-06
negative regulation of transcription from RNA polymerase II promoter 238 5.45 4.90E-10 1.43 3.54E-06
positive regulation of transcription from RNA polymerase II promoter 304 6.96 4.36E-09 1.34 3.16E-05
cellular response to hypoxia 48 1.10 2.53E-08 2.17 1.83E-04
negative regulation of transcription, DNA-templated 168 3.84 5.34E-08 1.46 3.86E-04
positive regulation of cell migration 76 1.74 6.07E-08 1.79 4.39E-04
transforming growth factor beta receptor signalling pathway 45 1.03 1.66E-07 2.12 0.001199
apoptotic process 181 4.14 9.54E-07 1.38 0.00688
peptidyl-serine phosphorylation 54 1.24 1.21E-06 1.87 0.008702
positive regulation of cell proliferation 151 3.46 3.27E-06 1.40 0.02335
protein autophosphorylation 67 1.53 4.51E-06 1.69 0.03212
G1/S transition of mitotic cell cycle 45 1.03 5.50E-06 1.91 0.03899
  1. Gene Ontology designations were generated via DAVID functional annotation. Only terms with a Bonferroni-adjusted pā€‰ā‰¤ā€‰0.05 are presented