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Table 2 KEGG pathways of the 42 differentially expressed miRNAs

From: Identification of potential biomarkers for diagnosis of pancreatic and biliary tract cancers by sequencing of serum microRNAs

KEGG Pathway Count % P-value Fold Enrichment Bonferroni
Pathways in cancer 158 3.62 1.19E-13 1.69 3.49E-11
FoxO signalling pathway 68 1.56 2.26E-11 2.14 6.65E-09
Glioma 40 0.92 3.67E-10 2.59 1.08E-07
Chronic myeloid leukaemia 42 0.96 1.22E-09 2.46 3.58E-07
Prostate cancer 47 1.08 5.20E-09 2.25 1.53E-06
Neurotrophin signalling pathway 56 1.28 7.08E-08 1.97 2.08E-05
Cell cycle 57 1.30 1.01E-07 1.94 2.97E-05
ErbB signalling pathway 44 1.01 1.37E-07 2.13 4.03E-05
Hepatitis B 63 1.44 2.44E-07 1.83 7.16E-05
p53 signalling pathway 36 0.82 3.64E-07 2.27 1.07E-04
PI3K-Akt signalling pathway 122 2.79 6.84E-07 1.49 2.01E-04
Viral carcinogenesis 80 1.83 1.08E-06 1.65 3.16E-04
Non-small cell lung cancer 31 0.71 1.24E-06 2.33 3.64E-04
Bladder cancer 25 0.57 1.76E-06 2.57 5.17E-04
Renal cell carcinoma 34 0.78 1.82E-06 2.21 5.35E-04
Pancreatic cancer 34 0.78 1.82E-06 2.21 5.35E-04
Proteoglycans in cancer 77 1.76 3.21E-06 1.62 9.43E-04
TGF-beta signalling pathway 40 0.92 3.82E-06 2.01 0.001123
MAPK signalling pathway 93 2.13 4.08E-06 1.54 0.001198
Signalling pathways regulating pluripotency of stem cells 58 1.33 4.85E-06 1.75 0.001425
Fc epsilon RI signalling pathway 34 0.78 6.49E-06 2.11 0.001905
Small cell lung cancer 39 0.89 1.52E-05 1.93 0.004457
Ras signalling pathway 82 1.88 2.03E-05 1.53 0.00595
Melanoma 34 0.78 2.05E-05 2.02 0.005999
T cell receptor signalling pathway 44 1.01 3.41E-05 1.80 0.009978
Endocytosis 90 2.06 4.31E-05 1.47 0.01259
Epstein-Barr virus infection 70 1.60 5.12E-05 1.55 0.014945
Hippo signalling pathway 58 1.33 6.68E-05 1.62 0.019459
Insulin signalling pathway 54 1.24 7.01E-05 1.65 0.020398
Thyroid hormone signalling pathway 46 1.05 1.15E-04 1.70 0.033145
Oestrogen signalling pathway 41 0.94 1.50E-04 1.75 0.043177
Acute myeloid leukaemia 27 0.62 1.56E-04 2.03 0.044742
Rap1 signalling pathway 74 1.69 1.58E-04 1.49 0.045381
Colorectal cancer 29 0.66 1.59E-04 1.97 0.045785
  1. KEGG pathways were generated by DAVID functional annotation. Only terms with a Bonferroni-adjusted pā€‰ā‰¤ā€‰0.05 are presented