Fig. 1

Clustering analysis of the differentially methylated CpG sites. a: Venn diagram of the DMCpG sites detected in the pre-surgery patients versus the controls and in the pre-surgery period versus the post-surgery period. Nine common sites indicated genes related to body weight changes. b: Supervised clustering of the nine CpGs that were differentially methylated in the pre-surgery patients as compered to the controls and which had their methylation profiles altered after the surgical procedure. c: Gene function of eight genes represented by the nine differentially methylated CpG sites