Fig. 2
From: Impact of cancer mutational signatures on transcription factor motifs in the human genome
Signature driven motif alterations: a Motif alteration signatures heatmap where the vertical axis corresponds to the 30 mutational signatures and the horizontal axis corresponds to the 512 motifs in JASPAR database. A kclust=4 PAM clustering performed over the TF alteration probability; b Cluster count statistics of each TF families with at least 5 members; c Familial binding profile of SOX-related motifs associated with PAM clusters