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Table 1 PGxSeq performance by sequencing cluster

From: Targeted next generation sequencing as a tool for precision medicine

  12-plex 24-plex
Subjects, n 52 183
Average reads (duplicates removed), per sample 1.01 M 0.54 M
DOC, mean (median) 213-fold ª (207-fold) ª 87.2-fold ª (84-fold) ª
Bases with mean DOC ≥1×, % 98.7 b 98.6 b
Bases with mean DOC ≥10×, % 98.0 b 96.8 b
Bases with mean DOC ≥20×, % 97.4 b 94.3 b
Bases with mean DOC ≥30×, % 96.8 b 90.9 b
  1. DOC depth of coverage
  2. ª Calculated across the 422 kb target sequence including all subjects each group
  3. b Represented as group mean for the percent base pairs (from 422 kb target sequence) with a DOC ≥1×, ≥ 10×, ≥ 20×, or ≥ 30 ×