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Table 1 PGxSeq performance by sequencing cluster

From: Targeted next generation sequencing as a tool for precision medicine

 

12-plex

24-plex

Subjects, n

52

183

Average reads (duplicates removed), per sample

1.01 M

0.54 M

DOC, mean (median)

213-fold ª (207-fold) ª

87.2-fold ª (84-fold) ª

Bases with mean DOC ≥1×, %

98.7 b

98.6 b

Bases with mean DOC ≥10×, %

98.0 b

96.8 b

Bases with mean DOC ≥20×, %

97.4 b

94.3 b

Bases with mean DOC ≥30×, %

96.8 b

90.9 b

  1. DOC depth of coverage
  2. ª Calculated across the 422 kb target sequence including all subjects each group
  3. b Represented as group mean for the percent base pairs (from 422 kb target sequence) with a DOC ≥1×, ≥ 10×, ≥ 20×, or ≥ 30 ×