Skip to main content
Fig. 7 | BMC Medical Genomics

Fig. 7

From: Novel secretome-to-transcriptome integrated or secreto-transcriptomic approach to reveal liquid biopsy biomarkers for predicting individualized prognosis of breast cancer patients

Fig. 7

a The interactive subnetworks of basal SeCEP genes. B,C) Correlation between Kaplan-Meier survival plots of the clinical outcomes and mRNA co-overexpression of indicated luminal SeCEP genes based on TCGA (b) and METABRIC (c) patient data. “N” refers to “Number of patients,” and “NE” refers to “Number of Events (Overall Survival status = DECEASED)”. Each plot shows the log-rank p-value and Hazard Ratio (HR) with 95% Confidence Interval (CI) between the two groups. The red line designates the patient subpopulation showing statistically significant overexpression of the indicated basal-specific genes (“altered”). The blue line designates the group of patients not showing statistically significant overexpression of the indicated basal-specific genes (“not altered”). Three of the four overexpressed genes are members of basal-specific interactive subnetworks

Back to article page