Table 3 Comparison of the genotype and allele distributions of HRH4 rs77485247
From: Histamine H4 receptor gene polymorphisms: a potential contributor to Meniere disease
SNP | MD group (n = 90) (n, [%]) | Control group (n = 90) (n, [%]) | χ2 | p | OR (95% CI) | Adjusted p* | Adjusted OR* (95% CI) |
|---|---|---|---|---|---|---|---|
rs77485247 T > A | |||||||
TT | 68 (75.6) | 80 (88.9) | 1 | 1 | |||
TA | 19 (21.5) | 9 (10.0) | 8.529 | 0.033 | 2.58 (1.34–4.97) | 0.027 | 2.06 (1.28–4.42) |
AA | 3 (3.3) | 1 (1.1) | 2.760 | 0.182 | 5.34 (0.58–48.54) | 0.031 | 3.45 (0.78–9.46) |
TA + AA | 22 (24.4) | 10 (11.1) | 10.380 | 0.012 | 2.75 (1.46–5.17) | 0.022 | 2.55 (1.39–4.76) |
T | 155 (86.7) | 169 (94.4) | 1 | 1 | |||
A | 25 (13.3) | 11 (5.6) | 11.570 | 0.011 | 2.67 (1.49–4.78) | 0.014 | 2.58 (1.74–5.03) |