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Table 3 Comparison of the genotype and allele distributions of HRH4 rs77485247

From: Histamine H4 receptor gene polymorphisms: a potential contributor to Meniere disease

SNP MD group
(n = 90)
(n, [%])
Control group
(n = 90)
(n, [%])
χ2 p OR (95% CI) Adjusted p* Adjusted OR* (95% CI)
rs77485247 T > A
 TT 68 (75.6) 80 (88.9)    1   1
 TA 19 (21.5) 9 (10.0) 8.529 0.033 2.58 (1.34–4.97) 0.027 2.06 (1.28–4.42)
 AA 3 (3.3) 1 (1.1) 2.760 0.182 5.34 (0.58–48.54) 0.031 3.45 (0.78–9.46)
 TA + AA 22 (24.4) 10 (11.1) 10.380 0.012 2.75 (1.46–5.17) 0.022 2.55 (1.39–4.76)
 T 155 (86.7) 169 (94.4)    1   1
 A 25 (13.3) 11 (5.6) 11.570 0.011 2.67 (1.49–4.78) 0.014 2.58 (1.74–5.03)
  1. CI confidence interval, HRH4 histamine H4 receptor, OR odds ratio, SNP single nucleotide polymorphism. * Adjusted for rheumatoid history, diabetes, asthma, osteoarthritis, anxiety, and depression