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Fig. 3 | BMC Medical Genomics

Fig. 3

From: DNA methylation status of TBX20 in patients with tetralogy of Fallot

Fig. 3

The impact of TBX20_ M1 region methylation on gene transcription activity. a The methylation status of BSP for the pGL3-TBX20_M1 region; b The methylation status of BSP for the Me-pGL3-TBX20_M1 region; c The luciferase activity assays for pGL3-Basic, pGL3-Promoter, pGL3-TBX20_M1 and Me-pGL3-TBX20_M1 in HEK 293 T and HL-1 cell lines, and the data are shown as the fold increase or decrease over the luciferase activity of pGL3-Promoter. The white circle represents unmethylated CpG sites, the black circle represents methylated CpG sites, *P < 0.05, **P < 0.01 (Mann-Whitney test)

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