Fig. 4From: DNA methylation status of TBX20 in patients with tetralogy of FallotSp1 promotes gene transcription activity by binding to the TBX20_M1 region. a Schematic of the DNA sequence of TBX20_M1 and Sp1 binding sites in this region. b Luciferase activity assays for pGL3-Basic, pGL3-TBX20_M1, pcDNA3.1-Sp1, Me-pGL3-TBX20_M1 and Mut-pGL3-TBX20_M1 in HEK 293āT and HL-1 cell lines. *Pā<ā0.05, **Pā<ā0.01 (Mann-Whitney test)Back to article page