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Fig. 4 | BMC Medical Genomics

Fig. 4

From: DNA methylation status of TBX20 in patients with tetralogy of Fallot

Fig. 4

Sp1 promotes gene transcription activity by binding to the TBX20_M1 region. a Schematic of the DNA sequence of TBX20_M1 and Sp1 binding sites in this region. b Luciferase activity assays for pGL3-Basic, pGL3-TBX20_M1, pcDNA3.1-Sp1, Me-pGL3-TBX20_M1 and Mut-pGL3-TBX20_M1 in HEK 293 T and HL-1 cell lines. *P < 0.05, **P < 0.01 (Mann-Whitney test)

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