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Table 1 Patient characteristics

From: Hepatic transcriptomic signatures of statin treatment are associated with impaired glucose homeostasis in severely obese patients

Characteristics n Values
Age [yr] 910 41.7 ± 11.7
Females 910 658 (72.3%)
Diabetic father 860 198 (23.0%)
Diabetic mother 881 277 (31.4%)
Obese father 870 312 (35.9%)
Obese mother 889 451 (50.7%)
Body mass index [kg/m2] 910 46.7 ± 8.7
Waist circumference [cm] 891 130.3 ± 17.7
Systolic blood pressure [mmHg] 908 135.9 ± 18.6
Diastolic blood pressure [mmHg] 908 76.3 ± 14.2
Diabetes 910 350 (38.5%)
Patients on antidiabetic drugs 892 281 (31.5%)
Patients with number of antidiabetic drugs 892  
 0 611 (68.5%)
 1 126 (14.1%)
 2 68 (7.6%)
 > 2 87 (9.8%)
Patients on insulin treatment 910 89 (9.8%)
Fasting blood glucose [mmol/L] 898 5.6 (5.1 to 6.8)
Fasting plasma insulin [mUI/L] 897 14.1 (9.3 to 21.1)
Fasting plasma C-peptide [ng/mL] 701 3.8 (3.0 to 4.9)
2 h blood glucose [mmol/L] 868 7.5 (6.0 to 11.2)
2 h plasma insulin [mUI/L] 866 57.3 (30.1 to 102.3)
2 h plasma C-peptide [ng/mL] 618 10.5 (7.5 to 13.1)
HbA1c [%] 902 5.9 (5.5 to 6.6)
HOMA2-B 896 116.7 (82.4 to 162.8)
HOMA2-IR 896 2.2 (1.4 to 3.2)
Hypertension 910 727 (79.9%)
Patients on anti-hypertensive drugs 910 386 (42.4%)
Total cholesterol [mmol/L] 903 4.9 ± 1.0
LDL cholesterol [mmol/L] 896 3.0 ± 0.8
HDL cholesterol [mmol/L] 903 1.1 ± 0.3
Triglycerides [mmol/L] 903 1.7 ± 1.4
Dyslipidemia 910 904 (99.3%)
Patients on antidyslipidemia drugs 910 217 (23.8)
Patients on statins 910 173 (19.0)
  1. Key anthropometric and metabolic parameters, medications and comorbidities of obese patients prior to surgery (n = number of patients with available data for the indicated parameter) are shown. Values are presented as numbers and percentage, mean ± SD or median (IQR) as appropriate. Abbreviations: HbA1c hemoglobin A1c, HOMA2-B homeostasis model assessment of β-cell function, HOMA2-IR homeostasis model assessment of insulin resistance, LDL low density lipoprotein, HDL high density lipoprotein, IQR interquartile range, SD standard deviation