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Table 5 Canonical Pathways identified by IPA software for 42 Housekeeping Genes Common to All Normalization Methods

From: Defining housekeeping genes suitable for RNA-seq analysis of the human allograft kidney biopsy tissue

Ingenuity Canonical Pathways -log(p-value) Ratio Molecules
Pyrimidine Ribonucleotides Interconversion 2.58 0.0444 NME4,SMARCAL1
Pyrimidine Ribonucleotides De Novo Biosynthesis 2.55 0.0426 NME4,SMARCAL1
Salvage Pathways of Pyrimidine Ribonucleotides 1.95 0.0211 NME4,POMK
Pyrimidine Deoxyribonucleotides De Novo Biosynthesis I 1.42 0.0435 NME4
Nucleotide Excision Repair Pathway 1.24 0.0286 POLR2B
Assembly of RNA Polymerase II Complex 1.09 0.02 POLR2B
Pyridoxal 5′-phosphate Salvage Pathway 0.983 0.0154 POMK
Mitotic Roles of Polo-Like Kinase 0.977 0.0152 ANAPC5
Protein Kinase A Signaling 0.836 0.005 PTPN14,ANAPC5
Androgen Signaling 0.767 0.00901 POLR2B
p38 MAPK Signaling 0.736 0.00833 MKNK1
RhoA Signaling 0.723 0.00806 RAPGEF6
Estrogen Receptor Signaling 0.711 0.00781 POLR2B
Hereditary Breast Cancer Signaling 0.665 0.00694 POLR2B
IL-12 Signaling and Production in Macrophages 0.66 0.00685 REL
Regulation of eIF4 and p70S6K Signaling 0.632 0.00637 MKNK1
CREB Signaling in Neurons 0.568 0.00538 POLR2B
RAR Activation 0.56 0.00526 REL
ERK/MAPK Signaling 0.541 0.005 MKNK1
Systemic Lupus Erythematosus Signaling 0.499 0.00444 SNRNP200
Huntington’s Disease Signaling 0.461 0.004 POLR2B
Protein Ubiquitination Pathway 0.441 0.00377 ANAPC5
Glucocorticoid Receptor Signaling 0.358 0.00295 POLR2B
Axonal Guidance Signaling 0.27 0.00221 MKNK1