Development and validation of GMI signature based random survival forest prognosis model to predict clinical outcome in acute myeloid leukemia

Shi, Mingguang; Xu, Guofu

doi:10.1186/s12920-019-0540-5

Table 3 The 23 differentially expressed genes

From: Development and validation of GMI signature based random survival forest prognosis model to predict clinical outcome in acute myeloid leukemia

Gene Symbol	Mean Signal of AML Group	Mean Signal of Control Group	t statistic	Fold Change	p-value	q-value	Gene Feature
SOX4	9.112336	7.219739	7.675507	3.713032	< 1 × 10–6	< 1 × 10–6	up
RASGRP1	5.83589	7.652658	−7.195507	−3.522911	< 1 × 10–6	< 1 × 10–6	down
BACH2	4.320585	6.060818	−8.152871	−3.340891	< 1 × 10–6	< 1 × 10–6	down
KLF12	6.133251	7.861214	−7.870257	−3.312596	< 1 × 10–6	< 1 × 10–6	down
LRIG1	4.728837	6.393224	−9.836949	−3.16979	< 1 × 10–6	< 1 × 10–6	down
ETS1	7.934244	9.498425	−7.305467	−2.957097	< 1 × 10–6	< 1 × 10–6	down
CA2	7.797592	6.234079	6.061318	2.955725	< 1 × 10–6	< 1 × 10–6	up
SGPP1	5.2489	6.809546	−10.216815	− 2.949861	< 1 × 10–6	< 1 × 10–6	down
AKTIP	5.928499	7.444547	−11.312356	− 2.860065	< 1 × 10–6	< 1 × 10–6	down
MGAT4A	6.147385	7.656076	−6.959608	− 2.845517	< 1 × 10–6	< 1 × 10–6	down
IGF1R	5.953049	7.435281	−9.157838	−2.793807	< 1 × 10–6	< 1 × 10–6	down
IGF2BP2	8.551588	7.080512	6.331802	2.772285	< 1 × 10–6	< 1 × 10–6	up
ATXN1	5.977417	7.443869	−11.143182	−2.763415	< 1 × 10–6	< 1 × 10–6	down
PLXNC1	6.920035	8.327643	−7.413724	−2.652969	< 1 × 10–6	< 1 × 10–6	down
PLEKHA1	5.191966	6.576699	−6.150913	−2.611237	< 1 × 10–6	< 1 × 10–6	down
PAG1	6.025085	7.409445	−6.906294	−2.61056	< 1 × 10–6	< 1 × 10–6	down
SNTB2	3.785427	5.155895	−6.769114	−2.585543	< 1 × 10–6	< 1 × 10–6	down
IGF2R	6.569925	7.933466	−6.300174	−2.573159	< 1 × 10–6	< 1 × 10–6	down
STK38	4.463917	5.809704	−6.984927	−2.541687	< 1 × 10–6	< 1 × 10–6	down
CDK6	6.572063	5.241319	9.134775	2.515324	< 1 × 10–6	< 1 × 10–6	up
LEF1	6.517115	8.211854	−5.602032	−3.237184	< 1 × 10–6	0.000002	down
ABLIM1	7.040753	8.373263	−5.375175	−2.518404	0.000001	0.000004	down
RORA	5.041835	6.718816	−5.269869	−3.197582	0.000001	0.000006	down

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