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Table 4 Univariate and multivariate Cox proportional hazard regression analyses of overall survival in TCGAPT. M, male; F, female; W, white; BA, Black or African American; GMI signature score was based on RSF model developed in TCGAPO

From: Development and validation of GMI signature based random survival forest prognosis model to predict clinical outcome in acute myeloid leukemia

  Univariate Multivariate
p value HR(95% CI) p value HR(95% CI)
Age 0.25 1.03 (0.98–1.09) 0.98 1.00 (0.94–1.07)
Gender (M or F) 0.62 1.16 (0.62–2.17) 0.78 1.09 (0.58–2.06)
Race (W or BA) 0.22 1.58 (0.73–3.44) 0.21 1.69 (0.75–3.84)
WBC count 0.02 1.79 (0.91–3.95) 0.03 1.83 (0.81–4.01)
NPM mutation 0.35 1.05 (0.99–1.12) 0.41 0.98 (0.89–1.09)
FLT3-ITD mutation 0.016 2.23 (1.18–4.09) 0.03 2.08 (1.04–3.95)
CEBPA mutation 0.85 1.18 (0.82–2.37) 0.67 1.36 (0.83–3.17)
WT1 mutation 0.78 1.31 (0.86–2.35) 0.83 0.87 (0.68–1.59)
GMI score 0.019 2.11 (1.11–4.03) 0.02 2.15 (1.08–4.29)