Fig. 3
From: Comprehensive genomic characterization of breast tumors with BRCA1 and BRCA2 mutations
a) Boxplots showing the number of deletions, tandem duplications, and interchromosomal translocations, in the genomes of 81 breast tumors. b) Probability distributions of the sizes of deletions and tandem duplications in the genomes of 81 breast tumors. c) Boxplots showing the fraction of structural variants in a tumor genome that contain regions of microhomology at the breakpoint, divided into deletions, tandem duplications and interchromosomal translocations, for 46 BRCA1/2-mutated tumors. The x-axis shows size of the structural variants. d) Manhattan plot with the y-axis showing the bonferroni-corrected p-value for enrichment of structural variants in 10-Mb long genomic bins, for 46 BRCA1/2-mutated tumors. The y-axis shows the position of the bin. Chromosomes are ordered from 1 to 22 followed by X