From: Comprehensive genomic characterization of breast tumors with BRCA1 and BRCA2 mutations
 | Gene | Chromosome | Length (bp) | Number of indels/SV breakpoints | Adjusted p-value | Adjusted p-value (corrected for copy number) | Adjusted p-value (corrected for copy number) BRCA1 only | Adjusted p-value (corrected for copy number) BRCA2 only |
---|---|---|---|---|---|---|---|---|
1 | RB1 | 13 | 176,159 | 17 | 1.31 × 10−9 | 1.69 × 10− 10 | 4.60 × 10− 9 | 1.00 |
2 | TP53 | 17 | 6986 | 5 | 5.48 × 10− 5 | 2.13 × 10− 5 | 6.17 × 10− 4 | 1.00 |
3 | PTEN | 10 | 101,523 | 10 | 1.45 × 10−4 | 7.53 × 10−5 | 1.66 × 10−2 | 1.00 |
4 | ETV6 | 12 | 240,919 | 13 | 0.00102 | 0.00243 | 4.17 × 10−5 | 1.00 |
5 | RUNX1 | 21 | 256,765 | 13 | 0.00210 | 0.00275 | 4.73 × 10−5 | 1.00 |
6 | KLHL8 | 4 | 32,021 | 6 | 0.00372 | 0.00293 | 3.73 × 10−4 | 1.00 |
7 | P4HB | 17 | 16,460 | 5 | 0.00380 | 0.00592 | 5.62 × 10−2 | 1.00 |
8 | NME7 | 1 | 234,926 | 12 | 0.00581 | 0.0695 | 1.83 × 10−3 | 1.00 |
9 | EFNA5 | 5 | 289,359 | 13 | 0.0080 | 0.00193 | 3.28 × 10−5 | 1.00 |
10 | ARGLU1 | 13 | 23,924 | 5 | 0.0233 | 0.0234 | 4.17 × 10−3 | 1.00 |
11 | DHX32 | 10 | 44,138 | 6 | 0.0236 | 0.0168 | 1.00 | 1.00 |