Skip to main content

Table 1 KEGG pathways enriched with a significant number of genes involved in CP

From: MicroRNA-374a, -4680, and -133b suppress cell proliferation through the regulation of genes associated with human cleft palate in cultured human palate cells

KEGG pathway CP genes in pathway
Pathways in cancer DVL3;ERBB2;FGF1;FGF2;FGF3;FGF4;FGF7;FGF8;FGF9;FGF10;FGFR1;FGFR3;FGFR2;GSTP1;ARNT;LEF1;PDGFRA;PTCH1;RARA;BMP2;BMP4;TGFA;TGFB1;TGFB3;WNT5A;WNT11;WNT10A;AXIN2;FGF18;WNT3A;FGF19;CDH1
Breast cancer DVL3;ERBB2;FGF1;FGF2;FGF3;FGF4;FGF7;FGF8;FGF9;FGF10;FGFR1;JAG2;LEF1;WNT5A;WNT11;WNT10A;AXIN2;FGF18;WNT3A;FGF19
Melanoma FGF1;FGF2;FGF3;FGF4;FGF7;FGF8;FGF9;FGF10;FGFR1;PDGFRA;FGF18;FGF19;CDH1
Hippo signaling pathway DVL3;FGF1;GDF6;LEF1;BMP2;BMP4;BMP7;TGFB1;TGFB3;WNT5A;WNT11;WNT10A;AXIN2;WNT3A;CDH1
Basal cell carcinoma DVL3;LEF1;PTCH1;BMP2;BMP4;WNT5A;WNT11;WNT10A;AXIN2;WNT3A
Signaling pathways regulating pluripotency of stem cells DVL3;FGF2;FGFR1;FGFR3;FGFR2;JARID2;PAX6;BMP2;BMP4;WNT5A;WNT11;WNT10A;AXIN2;WNT3A
Rap1 signaling pathway FGF1;FGF2;FGF3;FGF4;FGF7;FGF8;FGF9;FGF10;FGFR1;FGFR3;FGFR2;PDGFRA;FGF18;FGF19;CDH1
Regulation of actin cytoskeleton FGF1;FGF2;FGF3;FGF4;FGF7;FGF8;FGF9;FGF10;FGFR1;FGFR3;FGFR2;MYH9;PDGFRA;FGF18;FGF19
MAPK signaling pathway FGF1;FGF2;FGF3;FGF4;FGF7;FGF8;FGF9;FGF10;FGFR1;FGFR3;FGFR2;PDGFRA;TGFB1;TGFB3;FGF18;FGF19
Ras signaling pathway FGF1;FGF2;FGF3;FGF4;FGF7;FGF8;FGF9;FGF10;FGFR1;FGFR3;FGFR2;TBK1;PDGFRA;FGF18;FGF19
Chemical carcinogenesis NAT2;ADH1C;CYP1A1;CYP1B1;GSTP1;GSTT1;ARNT;UGT1A7;NAT1
One carbon pool by folate ALDH1L1;DHFR;MTHFD1;MTHFR;MTR
PI3K-Akt signaling pathway COL2A1;FGF1;FGF2;FGF3;FGF4;FGF7;FGF8;FGF9;FGF10;FGFR1;FGFR3;FGFR2;NOS3;PDGFRA;FGF18;FGF19
TGF-beta signaling pathway GDF6;BMP2;BMP4;BMP7;TGFB1;TGFB3;NOG
Prostate cancer ERBB2;FGFR1;FGFR2;GSTP1;LEF1;PDGFRA;TGFA
Cysteine and methionine metabolism AHCYL2;BHMT2;MTR;BHMT;CBS
Proteoglycans in cancer ERBB2;FGF2;FGFR1;PTCH1;SDC2;TGFB1;WNT5A;WNT11;WNT10A;WNT3A
Metabolism of xenobiotics by cytochrome P450 ADH1C;CYP1A1;CYP1B1;GSTP1;GSTT1;UGT1A7
Adherens junction ERBB2;FGFR1;LEF1;NECTIN1;NECTIN2;CDH1
EGFR tyrosine kinase inhibitor resistance ERBB2;FGF2;FGFR3;FGFR2;PDGFRA;TGFA
MicroRNAs in cancer CYP1B1;ERBB2;FGFR3;PDGFRA;ABCB1;TPM1;TP63;WNT3A
Caffeine metabolism NAT2;NAT1
Tryptophan metabolism TPH2;CYP1A1;CYP1B1;DDC
Central carbon metabolism in cancer ERBB2;FGFR1;FGFR3;FGFR2;PDGFRA
Melanogenesis DVL3;LEF1;WNT5A;WNT11;WNT10A;WNT3A
Arginine biosynthesis ASL;ASS1;NOS3
Wnt signaling pathway DVL3;LEF1;WNT5A;WNT11;WNT10A;AXIN2;WNT3A
Biosynthesis of amino acids ASL;ASS1;MTR;PAH;CBS