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Table 2 Comparison of SNV calling on 96 samples at 3 genomics positions. The 3 positions on the AR gene were screened by ddPCR used here as ground-truth. SINVICT Levels 5 and 6 and Levels 1, 2, 3 and 4 have been grouped as they give the same results. TP = True Positives, FP=False Positives, FN = False Negatives, TPR = True Positives Rate (Sensitivity), PPV=Positive Predictive Value (Precision), F1 = Harmonic mean of Precision and Sensitivity

From: Identification of single nucleotide variants using position-specific error estimation in deep sequencing data

 

TP

FP

FN

TPR

PPV

F1

AmpliSolve

 

19

2

11

63%

90%

74%

SiNVICT

Levels 1,2,3,4

17

0

13

57%

100%

73%

Levels 5,6

9

0

21

30%

100%

46%

deepSNV

 

15

3

15

50%

83%

62%