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Fig. 9 | BMC Medical Genomics

Fig. 9

From: Analysis of genetic networks regulating refractive eye development in collaborative cross progenitor strain mice reveals new genes and pathways underlying human myopia

Fig. 9

Top biological processes associated with genes linked to refractive eye development in mice and localized in known human myopia QTLs. a Chord diagram showing key genes (left semicircle) and top biological processes (right semicircle) associated with genes correlated with baseline refractive development in mice and localized in known human QTLs linked to myopia. b Chord diagram showing key genes (left semicircle) and top biological processes (right semicircle) for genes correlated with susceptibility to myopia in mice and localized in known human QTLs linked to myopia. Colored bars underneath gene names show up- or down-regulation of corresponding genes in either myopic mice versus hyperopic mice (A), or mice with high susceptibility to myopia versus mice with low susceptibility to myopia (B)

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