Criteria for reporting incidental findings in clinical exome sequencing – a focus group study on professional practices and perspectives in Belgian genetic centres

Table 1 Examples of interview questions

How do you describe an IF in a clinical context in your CMG, apart from following guidelines? What terminology do you use?
What differences do you see between IFs in array testing and in clinical ES?
What kind of IFs do you report, firstly from the laboratory to the clinician, and secondly from the clinician to the patient?
What kind of policy regarding IFs would you like to create in the future?
What impact do international guidelines on reporting IFs have on your own practice?
What difficulties do you experience in your practice regarding IFs or SFs? What are the great challenges in the evolution of IFs?
What is your current practice regarding a patient’s request to opt out of IFs?
How do you consider the intentional search for SFs?
What is your practice when new information is available about an IF, for example for recontacting patients?

Abbreviations used: CMG Centre for medical genetics, IF(s) Incidental finding(s), SF(s) Secondary finding(s), ES Exome sequencing.

ISSN: 1755-8794