From: Enhancer variants associated with Alzheimer’s disease affect gene expression via chromatin looping
GO | Category | Description | Count | % | Log10(P) | Log10(q) |
---|---|---|---|---|---|---|
GO:1902430 | GO Biological Processes | Negative regulation of amyloid-beta formation | 3 | 2.38 | -5.03 | -0.94 |
GO:0007271 | GO Biological Processes | Synaptic transmission, cholinergic | 4 | 3.17 | -4.47 | -0.91 |
R-HSA-1834949 | Reactome Gene Sets | Cytosolic sensors of pathogen-associated DNA | 5 | 3.97 | -4.34 | -0.89 |
GO:0002768 | GO Biological Processes | Immune response-regulating cell surface receptor signaling pathway | 11 | 8.73 | -4.29 | -0.89 |
GO:0072665 | GO Biological Processes | Protein localization to vacuole | 4 | 3.17 | -3.86 | -0.8 |
GO:0006353 | GO Biological Processes | DNA-templated transcription, termination | 5 | 3.97 | -3.45 | -0.59 |
GO:0016032 | GO Biological Processes | Viral process | 13 | 10.32 | -3.35 | -0.53 |
GO:0007169 | GO Biological Processes | Transmembrane receptor protein tyrosine kinase signaling pathway | 11 | 8.73 | -2.74 | -0.26 |
GO:0071466 | GO Biological Processes | Cellular response to xenobiotic stimulus | 5 | 3.97 | -2.62 | -0.2 |
GO:0007127 | GO Biological Processes | Meiosis I | 4 | 3.17 | -2.36 | -0.02 |
GO:0031329 | GO Biological Processes | Regulation of cellular catabolic process | 11 | 8.73 | -2.33 | -0.02 |
R-HSA-5653656 | Reactome Gene Sets | Vesicle-mediated transport | 10 | 7.94 | -2.31 | -0.01 |
M254 | Canonical Pathways | PID MYC REPRESS PATHWAY | 3 | 2.38 | -2.27 | 0 |
GO:0043547 | GO Biological Processes | Positive regulation of GTPase activity | 7 | 5.56 | -2.09 | 0 |
GO:0002274 | GO Biological Processes | Myeloid leukocyte activation | 9 | 7.14 | -2.06 | 0 |