Skip to main content
Fig. 10 | BMC Medical Genomics

Fig. 10

From: Transcriptome analysis of human monocytic cells infected with Burkholderia species and exploration of pentraxin-3 as part of the innate immune response against the organisms

Fig. 10

The role of PTX3-complement complexes in Bt phagocytosis by human monocytes. Pre-infection complexes between 10 μg/mL (a) or 30 μg/mL (b) of PTX3 and 107 Bt were used to infect 1 × 106 human monocytes in the presence of active complement (pooled NHS). Intracellular bacterial CFUs representative of phagocytosis were enumerated following 30 min of infection. An unpaired t-test did not reveal significant differences between phagocytosis for PTX3-pre-bound or unbound Bt. Data in (a) and (b) are each representative of n = 3 independent assays

Back to article page