Skip to main content
Fig. 7 | BMC Medical Genomics

Fig. 7

From: Transcriptome analysis of human monocytic cells infected with Burkholderia species and exploration of pentraxin-3 as part of the innate immune response against the organisms

Fig. 7

Opsonic antibodies fail to synergize with PTX3 in bolstering the lytic activity of complement towards Bt. Complexes of PTX3 and 107 Bt were subjected to (a) 10% or (b) 25% NHS +/− hyperimmune serum containing anti-Bm antibodies (Ab) also opsonic to Bt. Bacterial CFUs were enumerated at 0, 2, or 6 h post-serum exposure. Two-way ANOVA and Bonferroni multiple comparisons revealed no significant differences in CFUs between PTX3-bound or free bacteria. Data are representative of four to five assays per serum concentration

Back to article page