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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Integrative genomic analyses of APOBEC-mutational signature, expression and germline deletion of APOBEC3 genes, and immunogenicity in multiple cancer types

Fig. 3

Germline APOBEC3A/B deletion associated with APOBEC-mutational signature, neoantigen loads and relative composition of T cells (CD8+) in breast cancer. A significantly higher absolute (a) and relative (b) APOBEC-mutational signature, neoantigen loads (c) and relative composition of T cells (CD8+) (d) in samples predicted to carry homozygous and heterozygous deletion compared to samples predicted to have no deletion in breast cancer

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