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Table 5 Common response genes in HD BA9, HD+ BA9, and HD+ CAU, corresponds to middle intersection of Venn diagram in Fig. 2b

From: The caudate nucleus undergoes dramatic and unique transcriptional changes in human prodromal Huntington’s disease brain

Symbol Gene name (1) BM (1) L2FC (2) BM (2) L2FC (4) BM (4) L2FC
MAFF MAFF BZIP TF 385.63 1.5 605.27 2.56 1672.23 2.55
NFIL3 Nuclear Factor IL3 510.65 1.02 737.64 1.83 1379.75 2.48
BAG3 BCL2 Associated Athanogene 3 1451.15 1.71 1808.36 2.87 10878.27 3.0
HSPA6 Heat Shock Protein Family A (Hsp70) Member 6 155.97 2.65 4821.76 7.99 19890.86 5.73
HSPB1 Heat Shock Protein Family B (Small) Member 1 5352.69 1.81 6311.86 2.68 26621.0 2.56
ANGPT2 Angiopoeitin 2 278.17 1.68 202.34 1.45 819.36 2.59
C5AR1 Complement C5a Receptor 1 104.03 1.46 201.91 2.91 647.85 2.47
SERPINH1 Serpin Family H Member 1 491.4 1.49 1432.76 3.77 6758.88 2.92
HILPDA Hypoxia Inducible Lipid Droplet Associated 513.5 1.52 777.11 2.55 1946.98 2.27
GADD45B Growth Arrest And DNA Damage Inducible Beta 1345.54 1.56 2470.43 2.76 6656.73 1.9
DNAJB1 DnaJ Heat Shock Protein Family (Hsp40) Member B1 3833.3 1.05 9591.0 3.16 33978.66 3.37
HSPA1A Heat Shock Protein Family A (Hsp70) Member 1A 11803.6 1.69 24914.57 3.53 116944.49 3.27
PLIN2 Perilipin 2 360.3 0.84 477.77 2.21 1855.84 2.03
HSPA1B Heat Shock Protein Family A (Hsp70) Member 1B 10324.61 1.39 20241.7 2.86 84872.14 3.31
GADD45G Growth Arrest And DNA Damage Inducible Gamma 316.51 0.87 687.17 2.49 1374.17 1.88
ZC3H12A Zinc Finger CCCH-Type Containing 12A 35.5 0.84 101.95 3.14 283.56 2.55
C10orf10 DEPP1, Autophagy Regulator 1764.55 1.12 1236.25 1.99 11253.83 2.75
RRAD Ras Related Glycolysis Inhibitor And Calcium Channel Regulator 78.9 0.77 211.84 3.17 341.72 1.98
RGS16 Regulator Of G Protein Signaling 16 203.8 0.57 367.42 2.03 1198.58 2.24
  1. Base mean columns are the mean normalized counts from the correspondng analysis. L2FC is log 2 fold change estimated by DESeq2. BM - base mean (number of normalized counts) for the gene