Skip to main content

Table 6 Unique response genes in HD+ CAU, corresponds to only the green area diagram in Fig. 2b

From: The caudate nucleus undergoes dramatic and unique transcriptional changes in human prodromal Huntington’s disease brain

Symbol Gene name (1) BM (1) L2FC (2) BM (2) L2FC (4) BM (4) L2FC
CDHR4 Cadherin Related Family Member 4 3.93 -0.92 16.52 -1.0 47.49 -4.6
SIK1 Salt Inducible Kinase 1 172.19 0.96 351.77 2.86 452.63 3.11
CH507-9B2.1 Uncharacterized ncRNA gene 202.22 -0.98 172.02 2.0 292.54 5.39
TMIE Transmembrane Inner Ear 286.83 -0.21 387.23 0.07 380.24 2.33
DHFRP1 Dihydrofolate Reductase Pseudogene1 ND ND ND ND 21.19 7.87
RPS10-NUDT3 Read-through transcript 247.15 0.29 297.06 0.59 386.09 2.01
RSC1A1 Regulator Of Solute Carriers 1 ND ND 24.01 4.78 41.98 5.89
CCL19 C-C Motif Chemokine Ligand 19 34.45 -0.21 13.66 -2.58 166.21 -4.54
LRRC71 Leucine Rich Repeat Containing 71 11.97 0.61 33.61 0.13 67.87 -3.71
HSPH1 Heat Shock Protein Family H Member 1 9773.91 0.25 13966.0 0.6 20222.49 1.72
CX3CR1 C-X3-C Motif Chemokine Receptor 1 338.16 0.08 389.08 -0.81 472.45 -2.87
UBE2F-SCLY Read-through transcript 31.89 -0.18 45.88 0.83 48.19 4.65
NSFP1 N-Ethylmaleimide-Sensitive Factor Pseudogene 1 15.47 -1.69 51.57 -0.15 23.53 8.09
RPL17-C18orf32 Read-through transcript 275.3 -0.13 417.4 -0.36 523.12 2.23
THBS1 Thrombospondin 1 205.54 0.45 347.57 2.02 1448.89 2.64
DYDC2 DPY30 Domain Containing 2 51.37 -0.74 154.16 -1.57 251.82 -2.49
CBSL Cystathione-Beta-Synthase Like 754.57 0.3 746.02 2.38 789.33 3.06
PTGS2 Prostaglandin-Endoperoxide Synthase 2 313.94 0.01 390.51 1.64 291.52 2.1
LINC00473 Long Intergenic Non-Protein Coding RNA 473 60.5 0.41 68.35 1.52 75.01 3.55
CCDC33 Coiled-Coil Domain Containing 33 9.19 -1.08 37.91 -1.46 60.08 -5.15
SLC38A5 Solute Carrier Family 38 Member 5 505.13 -0.12 530.55 -0.83 641.39 -2.4
NPIPB15 Nuclear Pore Complex Interacting Protein Family Member B15 177.05 0.61 112.27 -3.21 231.41 -3.9
NPIPA8 Nuclear Pore Complex Interacting Protein Family Member A8 345.69 0.52 256.3 -1.61 82.36 -6.91
LTF Lactotransferrin 45.19 -0.52 152.43 -0.91 1448.49 3.24
RPL10P9 Ribosomal Protein L10 Pseudogene 9 29.12 0.64 76.79 2.08 107.51 6.1
RP5-850E9.3 Read-through transcript 106.96 -0.13 175.87 0.45 78.98 4.96
  1. Base mean columns are the mean normalized counts from the corresponding analysis. L2FC is log 2 fold change estimated by DESeq2. FDR <0.05 are considered significant for analyses (1) and (2). BM - base mean (number of normalized counts) for the gene. ND - genes not detected or too lowly abundant for consideration in the corresponding samples