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Fig. 1 | BMC Medical Genomics

Fig. 1

From: MECoRank: cancer driver genes discovery simultaneously evaluating the impact of SNVs and differential expression on transcriptional networks

Fig. 1

A schematic of MECoRank framework. a The data we used including gene expression of cancer and normal patients, somatic SNVs and PPI network. b The left partition of bipartite graph represents an individual patient’s expression set U where the transition matrices WUU indicates the relations in U. The right of the bipartite graph represents the patient’s mutation set V where the transition matrices WVU indicates the interactions between U and V. c We can obtain a score matrix in which each gene of every patient has a score. d We used the Condorcet voting to obtain the final rank of the genes

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