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Fig. 5 | BMC Medical Genomics

Fig. 5

From: HiSSI: high-order SNP-SNP interactions detection based on efficient significant pattern and differential evolution

Fig. 5

Powers of different approaches on two three-locus disease models (Models 4–5) with 1000 SNPs. Powers of DCHE, DECMDR, EDCF, HiSSI and HiSSI-BC on two three-locus models under different minor allele frequency (MAF) and linkage disequilibrium (LD) with 1000 SNPs, 2000 and 4000 samples; HiSSI-BC is a variant of HiSSI that uses the Bonferroni correction to obtain the corrected significant threshold. N0 is the number of controls, N1 is the number of cases, and M is the number of SNPs. The absence of a bar indicates no power. (a) Model4; (b) Model5

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