Table 2 Significant two-locus and three-locus combinations identified by HiSSI on WTCCC BC data

(rs1108842, rs2289247)

(chr3: GNL3, chr3: GNL3)

(1.139×10⁻²,5.981×10⁻¹)

6.048×10⁻⁴⁵

(rs1130643, rs10017772)

(chr4: SPARCL1, chr4: DCHS2)

(2.823×10⁻¹,3.830×10⁻¹)

2.865×10⁻⁸

(rs3761967, rs715748)

(chr5: BDP1, chr5: BDP1)

(1.720×10⁻¹,4.073×10⁻¹)

1.238×10⁻⁵⁴

(rs2242665, rs2856705)

(chr6: SLC44A4, chr6: *)

(3.484×10⁻⁴,6.178×10⁻⁸)

4.369×10⁻²⁵

(rs1801197, rs6971091)

(chr7: CALCR, chr7: FAM71F1)

(4.983×10⁻²,6.728×10⁻¹)

2.504×10⁻¹⁰

(rs365990, rs7158731)

(chr14: MYH6, chr14: ZNF839)

(8.807×10⁻³,3.319×10⁻³)

1.636×10⁻⁶

(rs8059973, rs3785181)

(chr16: DBNDD1, chr16: GAS11)

(3.019×10⁻⁴,1.464×10⁻³)

4.050×10⁻⁷

(rs2822558, rs2822787)

(chr21: ABCC13, chr21: SAMSN1-AS1)

(6.630×10⁻³,1.662×10⁻¹)

4.207×10⁻²¹

(rs879882, rs2523608, rs805262)

(chr6: POU5F1, chr6: HLA-B, chr6: BAG6)

(2.711×10⁻¹,7.096×10⁻¹,5.836×10⁻⁴)

1.030×10⁻¹¹