Fig. 2
From: Integrative molecular analysis of metastatic hepatocellular carcinoma
Candidate driver genes regulated by CNVs and promoter DNA methylations. a The correlations between gene expressions and CNVs/promoter DNA methylations. b Scatterplot of the correlations. A few top candidate drivers, whose expressions are significantly affected both by CNVs and promoter DNA methylations, are highlighted. c A hotspot genomic region of candidate driver genes (chromosome 11q13). The first row shows the accumulated CNVs, the second shows the differential DNA methylation levels in promoters, the third shows the differential gene expressions, the fourth indicates candidate genetic driver genes whose expressions are positively correlated with CNVs and the fifth indicates candidate epigenetic driver genes whose expressions are negatively correlated with promoter DNA methylations