Fig. 4

The individualized differential expression patterns between primary tumors and PVTTs identified by IDASeq. a The number of differentially expressed genes in each patient (q-value < 0.1). The log2 fold changes of recurrently differentially expressed genes in b) focal adhesion, c cytochrome P450 family, and d) amino acids metabolism. e Survival analyses based on CPS1, HPD, and TAT expressions. High (red) and low (blue) expression groups are split by median expressions. f Differential expression analyses of CPS1, HPD, and TAT between vascular invasion and non-invasion patients. The invasion group is further divided as micro-vascular invasion (second column) and macro-vascular invasion (third column) in TCGA dataset