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Fig. 3 | BMC Medical Genomics

Fig. 3

From: A novel genomic panel as an adjunctive diagnostic tool for the characterization and profiling of breast Fibroepithelial lesions

Fig. 3

The genetic landscape of breast fibroepithelial lesions. The distribution of the recurrently mutated genes was identified through the targeted sequencing of 211 fibroepithelial lesions. Top, the method of biopsy is identified (core biopsy, grey; surgical excision, maroon). There were 179 core biopsies and 32 surgical excisions, of which, three were paired (paired biopsies, black). The histological diagnoses of the biopsies were as described: fibroadenoma (FA), phyllodes tumor (PT), benign (BEN) PT, borderline (BDR) PT and malignant (MAL) PT. In total, there were 167 FAs, 24 BEN PTs, 14 BDR PTs and 6 MAL PTs. The colored rectangles indicate the type of somatic mutations observed in the lesions. The colored dots signify additional mutations observed. The 16 genes used in the targeted sequencing of these lesions are listed on the left

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BMC Medical Genomics

ISSN: 1755-8794

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