Table 5 A summary of the univariate analyses performed to understand the effect of each potential predictor in the classification of the fibroepithelial lesions. Predictors (Ɨ), with p < 0.10, were included in the multivariate analysis
Predictors | Odds Ratio (OR) | 95% Confidence Interval (CI) | p value |
|---|---|---|---|
Genes | |||
 MED12Ɨ | 1.95 | 0.99 to 3.84 | 0.054 |
 TERT promoterƗ | 24.50 | 8.95 to 67.07 | < 0.001 |
 KMT2D | 1.10 | 0.46 to 2.60 | 0.836 |
 RARAƗ | 13.59 | 4.52 to 40.84 | < 0.001 |
 SETD2 | 1.53 | 0.72 to 3.22 | 0.266 |
 FLNAƗ | 3.96 | 1.73 to 9.06 | 0.001 |
 NF1 | 1.09 | 0.22 to 5.43 | 0.918 |
 EGFR | 2.98 | 0.64 to 13.85 | 0.163 |
 RB1Ɨ | 4.24 | 1.29 to 13.86 | 0.017 |
 TP53Ɨ | 8.25 | 1.46 to 46.64 | 0.017 |
 PIK3CA | 1.94 | 0.34 to 10.96 | 0.453 |
 BCOR | 1.94 | 0.34 to 10.96 | 0.453 |
 PTEN | Excluded, frequency < 5 | ||
 ERBB4 | 1.92 | 0.17 to 21.66 | 0.598 |
 MAP3K1 | Excluded, frequency < 5 | ||
 IGF1R | Excluded, frequency < 5 | ||
Mutation types | |||
 Missense | 1.76 | 0.81 to 3.82 | 0.152 |
 PromoterƗ | 24.50 | 8.95 to 67.07 | < 0.001 |
 Non Frameshift | 1.19 | 0.54 to 2.67 | 0.664 |
 FrameshiftƗ | 7.20 | 2.23 to 23.30 | 0.001 |
 NonsenseƗ | 26.20 | 3.06 to 224.10 | 0.003 |
 Splice site | Excluded, frequency < 5 | ||
Mutation count | |||
 Mutation count (≥3) Ɨ | 13.11 | 5.85 to 29.40 | < 0.001 |