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Table 4 Genotype distribution of the rs9301654 polymorphism in different population

From: A functional polymorphism in the promoter of miR-17-92 cluster is associated with decreased risk of ischemic stroke

 

Genotypes (n, %)

Alleles (n, %)

 

Population

n

AA

GA

GG

A

G

Ethnic group

Our data

397

235 (59.2)

141 (35.5)

21 (5.3)

611 (77.0)

183 (23.0)

Asian

HapMap-HCB

86

56 (65.1)

24 (27.9)

6 (7)

136 (79.1)

36 (20.9)

Asian

HapMap-JPTΔ

172

84 (48.8)

74 (43.0)

14 (8.1)

242 (70.3)

102 (29.7)

Asian

HapMap-YRI

226

131 (58.0)

82 (36.3)

13 (5.8)

344 (76.1)

108 (23.9)

African

HapMap-ASWΔ

98

43 (43.9)

44 (44.9)

11 (11.2)

130 (66.3)

66 (33.7)

African

HapMap-CHB

82

50 (61.0)

30 (36.6)

2 (2.4)

130 (79.3)

34 (20.7)

Asian

HapMap-CHD

170

112 (65.9)

50 (29.4)

8 (4.7)

274 (80.6)

66 (19.4)

Asian

HapMap-GIHΔ

176

134 (76.1)

42 (23.9)

310 (88.1)

42 (11.9)

Asian

HapMap-LWKΔ

180

130 (72.2)

42 (23.3)

8 (4.4)

302 (83.9)

58 (16.1)

Asian

HapMap-MEXΔ

100

88 (88.0)

11 (11.0)

1 (1.0)

187 (93.5)

13 (6.5)

North America

HapMap-MKKΔ

286

132 (46.2)

126 (44.1)

28 (9.8)

390 (68.2)

182 (31.8)

African

HapMap-TSIΔ

176

134 (76.1)

42 (23.9)

310 (88.1)

42 (11.9)

European

  1. HCB Han Chinese in Beijing, China, JPT Japanese in Tokyo, Japan YRI Yoruba in Ibadan, Nigeria, ASW African ancestry in Southwest USA, CHB Han Chinese in Beijing, China, CHD Chinese in Metropolitan Denver, Colorado, GIH Gujarati Indians in Houston, Texas, LWK Luhya in Webuye, Kenya, MEX Mexican ancestry in Los Angeles, California, MKK Maasai in Kinyawa, Kenya, TSI Toscans in Italy
  2. Δ: Comparing with our present data, P < 0.05