Skip to main content

Table 5 MsigDB molecular signatures enrichment analysis for genes differentially expressed between MM and CM patients

From: Gene expression profiling in blood from cerebral malaria patients and mild malaria patients living in Senegal

IDa

Description

P value

FDR

GSE14308

Genes up-regulated in comparison of Th2 cells versus naive CD4 [GeneID = 620] T cells.

2,98E-07

1,42E-04

GSE17721

Genes up-regulated in comparison of control dendritic cells (DC) at 12 h versus those stimulated with LPS (TLR4 agonist) at 12 h.

7,81E-06

1,07E-03

GSE14769

Genes up-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 120 min.

7,52E-06

1,10E-03

GSE14000

Genes up-regulated in comparison of dendritic cells (DC) before and 4 h after LPS (TLR4 agonist) stimulation.

1,65E-05

1,75E-03

GSE11864

Genes up-regulated in comparison of untreated macrophages versus those cultured with M-CSF [GeneID = 1435] and IFNG [GeneID = 3458].

1,93E-05

1,76E-03

GSE18791

Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 10 h versus cDCs infected with Newcastle disease virus (NDV) at 10 h.

1,04E-04

5,50E-03

GSE17974

Genes up-regulated in comparison of CD4 [GeneID = 920] T cells treated with IL4 [GeneID = 3565] and anti-IL12 at 0.5 h versus those at 72 h.

4,14E-04

1,47E-02

GSE15930

Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 24 h after stimulation with IL12 .

5,62E-04

1,79E-02

GSE22886

Genes up-regulated in comparison of naive CD4 [GeneID = 920] T cells versus stimulated CD4 [GeneID = 920] Th2 cells at 12 h.

7,93E-04

2,13E-02

GSE25087

Genes down-regulated in comparison of fetal regulatory T cell (Treg) versus fetal conventional T cells.

1,45E-03

2,75E-02

GSE24634

Genes up-regulated in comparison of CD25+ T cells treated with IL4 [GeneID = 3565] versus CD25- T cells treated with IL4 [GeneID = 3565] at day 5.

1,69E-03

3,11E-02

GSE9988

Genes down-regulated in comparison of monocytes treated with anti-TREM1 [GeneID = 54,210] and 5000 ng/ml LPS (TLR4 agonist) versus monocytes treated with control IgG.

2,55E-03

3,77E-02

GSE14308

Genes down-regulated in comparison of Th1 cells versus induced regulatory T cell (Treg).

3,90E-03

4,81E-02

GSE13229

Genes down-regulated in comparison of mature NK cells versus intermediate mature NK cells.

4,43E-03

5,26E-02

GSE13306

Genes up-regulated in comparison of CD4 [GeneID = 920] T cells activated with lamina propria dendritic cells versus regulatory T cell (Treg).

7,03E-03

7,10E-02

GSE26495

Genes up-regulated in comparison of naive CD8 T cells versus PD-1 low CD8 T cells.

8,22E-03

7,74E-02

GSE17580

Genes down-regulated in comparison of regulatory T cell (Treg) from uninfected mice versus regulatory T cell (Treg) from mice infected with S. mansoni.

8,92E-03

7,85E-02

GSE14308

Genes up-regulated in comparison of Th2 cells versus natural regulatory T cell (Treg).

8,77E-03

7,86E-02

GSE22886

Genes up-regulated in comparison of naive CD4 [GeneID = 920] T cells versus stimulated CD4 [GeneID = 920] Th1 cells at 12 h.

1,04E-02

8,67E-02

GSE9650

Genes up-regulated in comparison of effector CD8 T cells versus exhausted CD8 T cells.

1,64E-05

1,84E-03

GSE25087

Genes down-regulated in comparison of fetal regulatory T cell (Treg) versus fetal conventional T cells.

1,45E-03

2,75E-02

  1. aMsigDB molecular signatures have been selected among those that were significant