Table 1 The haplotype in USH2A gene in 11 embryos
Embryo | ADO | Haplotypes in USH2A gene | Genotypes in USH2A gene | Numbers of Informative SNPs supported each haplotype in each embryo | |||
|---|---|---|---|---|---|---|---|
M-Hap A | M-Hap B | F-Hap A | F-Hap B | ||||
Embryo 1 | 0.00% | M-Hap A/F-Hap B | p.Ser2251Ter/N | 97 | 0 | 0 | 282 |
Embryo 2 | 0.00% | M-Hap B/F-Hap A | c.1144-2A > C/c.10740 + 7G > A | 0 | 66 | 168 | 0 |
Embryo 3 | 31.71% | M-Hap B/F-Hap A | c.1144-2A > C/c.10740 + 7G > A | 0 | 32 | 118 | 0 |
Embryo 4 | 0.00% | M-Hap B/F-Hap A | c.1144-2A > C/c.10740 + 7G > A | 0 | 82 | 183 | 0 |
Embryo 5 | 0.00% | M-Hap B/F-Hap A | c.1144-2A > C/c.10740 + 7G > A | 0 | 82 | 185 | 0 |
Embryo 6 | 12.20% | M-Hap B/F-Hap A | c.1144-2A > C/c.10740 + 7G > A | 0 | 58 | 117 | 0 |
Embryo 7 | 0.00% | M-Hap A/F-Hap A | p.Ser2251Ter/c.10740 + 7G > A | 94 | 2 | 185 | 0 |
Embryo 8 | 4.88% | M-Hap A/ F-Hap B | p.Ser2251Ter/N | 95 | 0 | 0 | 276 |
Embryo 9 | 0.00% | M-Hap B/F-Hap B | c.1144-2A > C/N | 0 | 83 | 0 | 282 |
Embryo10 | 0.00% | M-Hap B/F-Hap A | c.1144-2A > C/c.10740 + 7G > A | 0 | 81 | 181 | 0 |
Embryo11 | 14.63% | M-Hap A/F-Hap B | p.Ser2251Ter/N | 34 | 0 | 0 | 77 |