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Table 1 Clinical characteristics

From: Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis

  SSc (N = 9) Controls (N = 9)
Mean or % SD or N Mean or % SD or N
Age, years 52.8 16.2 45.2 20.0
Female, % 100% 9 44.4% 4
Ethnicity, %
 Caucasian 77.8% 7 66.7% 6
 Asian 22.2% 2 22.2% 2
 Other 0 11.1% 1
Smoking, %
 Current 11.1% 1 0
 Past 22.2% 2 22.2% 2
 Never 55.6% 5 77.8% 7
 Unknown 11.1% 1 0
Disease duration, years 10.4 7.0   
Interstitial lung disease, % 11.1% 1   
Arthritis, % 11.1% 1   
Myositis, % 22.2% 2   
Raynaud’s, % 100% 9   
Anti-nuclear antibodies
 Titer ≥1:80, % 100% 9   
 Titer ≥1:160, % 66.7% 6   
 Titer ≥1:640, % 55.6% 5   
Blood biochemical indices
 C-reactive protein (CRP), mg/L 29.5 65.3   
 Erythrocyte sedimentation rate, mm/hr 23.7 14.1   
 Abs. whole blood cell (WBC), K/ μ L 8.2 4.6   
 Abs. lymphocytes, K/ μ L 1.6 0.7   
 Abs. monocytes, K/ μ L 0.7 0.7   
Disease-specific variables
 Limited skin disease 33.3% 3   
 Diffuse skin disease 66.7% 6   
Immunosuppressive medication§, % 33.3% 3   
  1. Over-dispersion due to extreme values
  2. § Methotrexate and/or Mycophenolate