Table 3 Top five networks influenced by CpG differential methylation

Embryonic Development, Organismal Development, Reproductive System Development and Function

AGO2, AP2A2, BOP1, CACHD1, CENPS/CENPS-CORT, CEP120, Ck2, CSNK1D, CSNK1E, ESR1, FAAP20, FAM83D, FAN1, FBXW11, FGFR1OP, HPCAL1, Hsp70, INPP5B, KTN1, MAP3K9, mir-363, NIN, phosphatase, PPFIBP1, PSD4, RAPGEF5, RBM19, RNF166, Rnr, SAMD11, Smad2/3, Ubiquitin, UMODL1, USP2, WRAP73

Cancer, Connective Tissue Disorders, Organismal Injury and Abnormalities

Akt, ANKRD11, CEACAM3, CHIA, COL23A1, COL4A1, COL5A1, collagen, Dynamin, Eph Receptor, EPHA1, EPHA10, GNB1L, GTPase, HOOK2, JINK1/2, KIAA1217, KIF26B, KSR1, Laminin (family), LIMS1, MAGI1, MTORC2, NAV1, NCK, NCK2, PARVB, PBXIP1, PI3K p85, PRDM16, PTPRN2, RPTOR, SH3BP4, SH3PXD2B, SH3RF3

Cell Morphology, Cellular Assembly and Organization, Cellular Development

BCAR3, CK1, CLEC4C, DNAJC2, ERK1/2, Fgf, FXN, GALNT2, GSPT1, Hdac, HSP, HSPA12B, KCNN2, KCNN3, KCNQ3, LIN54, MARCH1, MHC Class II (complex), MYL12A, Ngf, NTF3, PLC gamma, potassium channel, Ral, RALGDS, ROBO1, ROR2, SH3BP2, SLC7A8, TFDP1, TUSC3, Vla-4, Wnt, WNT9A, histone deacetylase

Gene Expression, Connective Tissue Disorders, Immunological Disease

CBS/CBSL, Ctbp, CTBP2, ETV6, GATAD2B, GPC6, Growth hormone, HDAC4, HDL-cholesterol, hemoglobin, HIPK2, HISTONE, Histone h4, Immunoglobulin, Jnk, KCNJ6, LDL, LDL-cholesterol, MECP2, MTHFD1L, N-cor, NCOR2, NFATC1, NPC2, Nr1h, NTM, PF4, Pias, PON1, POU2F1, SBNO2, STAT5a/b, TTC39B, VSX1, ZBTB16

Developmental Disorder, Hereditary Disorder, Organismal Injury and Abnormalities

Alpha tubulin, ANO1, ATP11A, ATP5MC2, BETA TUBULIN, caspase, Cyclin E, DLGAP1, DLGAP2, DYSF, ERK, FMN1, FTSJ1, Hsp27, Hsp90, Insulin, KCNG2, MAP3K20, Mek, NLRP12, NNAT, p70 S6k, PACRG, PARP, Pde, PDE9A, PIWIL1, Ppp2c, PRKN, Proinsulin, RGPD4 (includes others), Sos, TRPV2, XAF1, ZBTB17